Social Oocyte Freezing: A Boon for Aging Females

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Social oocyte freezing

Reproductive aging has become an important social and medical development. the trend to delay childbearing in modern societies to a much less fecund age often confronts women with difficulties to conceive. the aging of the ovary resulting in a decline in the total number of oocytes and in their quality cannot be undone. However, it often engenders unrealistic expectations of what modern fertili...

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Apoptosis Maintains Oocyte Quality in Aging Caenorhabditis elegans Females

In women, oocytes arrest development at the end of prophase of meiosis I and remain quiescent for years. Over time, the quality and quantity of these oocytes decreases, resulting in fewer pregnancies and an increased occurrence of birth defects. We used the nematode Caenorhabditis elegans to study how oocyte quality is regulated during aging. To assay quality, we determine the fraction of oocyt...

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Theoretical considerations for oocyte cryopreservation by freezing Introduction

Attempts to cryopreserve oocytes by freezing have, to date, been based mostly on empirical approaches rather than on basic principles, and perhaps in part for this reason have not been very successful. Theoretical considerations suggest some fairly ‘heretical’ conclusions. The concentrations of permeating cryoprotectants employed in past studies have probably been inadequate, and the choice of ...

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Elective oocyte freezing for the preservation of fertility

Oocyte cryopreservation has recently emerged as an option for women to preserve their fertility for medical (e.g. treatable malignancy) or elective indications (e.g. advancing age). This report describes an IRBapproved study of over 200 oocyte cryopreservation cycles at one center. Patients presenting for oocyte cryopreservation (January 2005 to 2010) were analyzed for day 3 follicle stimulatin...

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Expanding reproductive lifespan: a cost-effectiveness study on oocyte freezing.

BACKGROUND The average age of women bearing their first child has increased strongly. This is an important reproductive health problem as fertility declines with increasing female age. Unfortunately, IVF using fresh oocytes cannot compensate for this age-related fertility decline. Oocyte freezing could be a solution. METHODS We used the Markov model to estimate the cost-effectiveness of three...

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ژورنال

عنوان ژورنال: International Journal of Infertility & Fetal Medicine

سال: 2018

ISSN: 2229-3817,2229-3833

DOI: 10.5005/jp-journals-10016-1169